Process Chemistry News
Specialised Session at Modern Synthetic Methods & Chiral USA, Orlando May 2014.
The session consisted of 5 presentations which are summarised below with the summaries concentrating specifically on the metathesis reactions presented, although several speakers also described some very interesting chemistry used to make the metathesis substrates.
I came across an intriguing paper (T Sela and A Vigalok, Org Lett, 2014, 16, 1964) where the authors investigated a number of reactions ‘on water’ and compared them when conducted ‘on liquids’ to ascertain if there was a particular attribute that water brought to the chemistry.
There have of course been many many papers in recent years discussing flow chemistry and it applications across scales from discovery through to full commercial manufacture.