October 2003 Issue No. 11
Highlights from the 8th International Conference on Orangic Process Research & Development, Barcelona, Spain, 7 -10 September 2003
Efficient Synthesis of the Kappa-Opiod Receptor Antagonist CH-15,161
Process Aspects of Asymmetric Hydrogenation
Process Development of Cryptophycins: Journey Toward Symplicity
New Concepts in Molecular Synthesis:Cascade Catalysis and Multi-Step Conversions in Concert
Lu 02-030: Developing a scalable and viable route to manufacture the drug candidate 4,5,6,7-tetrahydroisoxazolo[5,4-9c]pyridin-3-ol, hydrochloride (THIP)
Ceramide II. From Sample to Process
Radical Transformations in the Macrolide Series: Challenges for Process R & D
Development and Scale-up of Synthetic Routes to AR-C123196
The Chemical Development of a Selective Alpha-Blocker, UK-338,003
Homogeneous Catalysis: From Coors to Heineken
Highlights from the Development of Processes for the Synthesis of 2,6-Diaminopurine Nucleosides
Synthesis, Scale-up and Use of a New Class of Halex Catalysis
From Naproxen to Gabapentin: Twenty Years of Development of Scaleable Routes for Active Ingredients in Zambon
DioRaSSP: Diosynth Rapid Solution Synthesis of Peptides
A Practical Synthesis and Process for the Production of a New HIV Protease Inhibitor
Dihydro-7-benzofurancarboxylic Acid, An Intermediate in the Synthesis of the Enterokinetic Agent R 108512
Creativity Through Diversity in Process Development
Rapid Scale-Up of the Matrix Metalloproteinase Inhibitor CH5902: Process Safety and Route Development Considerations