IN THIS ISSUE...

The first E-Newsletter of 2004 contains highlights from the
Chiral USA 2003 held at the Intercontinental Hotel, Chicago, USA on October 21st and 22nd.

Process Development for a Novel Muscarinic M3 Receptor Antagonist

Catalytic Enantioselective Reductive Coupling Reactions

Asymmetric Synthesis in Medicinal Chemistry Collaborations

Trends in Pharmaceutical Biocatalysis - Discovery, Development and Manufacturing

Controlling and Exploiting Conformation in Semi-Rigid Molecules

Enantioselective Oxidative Biaryl Coupling and Asymmetric Ketoester Allylation

An Asymmetric Hydrogenation Based Process to Atorvastatin

Production of Sugar Polyols by Fermentation

Organocatalysis: A Ketone Catalysed Asymmetric Epoxidation of Olefins

Recent Advances in the Process Chemsitry of Novel AIDS Therapeutics

Anchored Homogeneous Catalysts: High TON Applications

Industrial Genetics: Efficient New Bioprocesses to Deracemise Amino Acids and Amines

Fascinating Excursions into Chiral Chemistry: An Insider's Perspective

Industrially Successful Asymmetric Catalysis - Proven Concepts and Learnings

Catalytic Generation of Chiral Magnesium Enolates from
1,3-Dicarbonyl Compounds: Application to the Synthesis of ABT-546

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