IN THIS ISSUE...

More highlights from the 7th International Conference on Organic Process Research and Development,
New Orleans, March 16-19, 2003

Monolith Loop Reactor

Uses and Abuses of Statistical Design

Synthesis and Scale Up of Tissue
Selective EstrogeneZK 186619

The Impact of a tert-Butyl Group

Synthesis and Scale Up of Chiral Alcohols and Epoxides

BoPhoz Ligands for Asymmetric Catalysis

PLUS

Photochemistry - New Light
on an Old Problem

Fluorous Phase Catalysis

Microwave Technology

Automation at Degussa

Variable Residence Time Reactor

This Month's Topical Tip

Pd(OAc)₂ is a very effective catalyst for Heck Reactions. Re-use of the Pd-black residue from previous reactions shows very low activity.

However, addition of I₂ or Br₂ completely restores the original activity.

presented by Bert Zeegers (DSM)
at Scientific Update's Chiral Europe Conference in May 2003